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This article does not provide any personal-use preparation, dosing, administration, or non-research application instructions

Vitamin B12 Deficiency Causes of vitamin B12 deficiency include difficulty absorbing vitamin B12 from food, lack of intrinsic factor (e.g., because of pernicious anemia), surgery in the gastrointestinal tract, prolonged use of certain medications (e.g., metformin or proton pump inhibitors), and dietary deficiency

Some people notice a subtle energy boost or mood lift within 2448 hours , while others may experience more gradual, cumulative results with an ongoing injection protocol

However, the efficacy of such a treatment can be limited, as conventional routes of analgesic administration (oral, intravenous, etc.) are often associated with numerous adverse effects