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Some patients may experience a transient increase in acne or rosacea-like skin reactions, thought to be related to the effects of vitamin B12 on skin bacteria, though this is uncommon and typically mild

[DOI] [PubMed] [Google Scholar] 147.Bowyer RC, Rowston WM, Jehanli AM, Lacey JH, Hermon-Taylor J

However, most of this research has been conducted in animal models, and human safety and efficacy data are limited

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