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Description
By this point, most patients have completed their initial dose titration and are approaching or sitting at the 7.5 to 10 mg range

Constipation adds to these troubles, because straining during a bowel movement increases pressure in the anal canal and pushes the hemorrhoids against the sphincter muscle
Some people feel it shortly after their first few doses, while others may not notice any pain until they have been on the medication for weeks or even months

If you ever have doubts about storage or use, its always best to follow your healthcare providers instructions or check the medication guide
