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With Bydureons remarkable profile (nearly two points in A1c reduction, weight loss, much less nausea than Byetta, convenience of a once-weekly shot), we would have thought at least the FDA could have approved the drug in a population that did not include individuals with impaired renal systems, assuming this is the population in question

Comparison of diabetes medications used by adults with commercial insurance vs Medicare advantage, 2016 to 2019

PLoS One 17:e0266859

These results indicate that liraglutide exhibits strong protective properties against PA-induced skeletal muscle lipotoxicity
