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Description
These fragments were subcloned into the Mlu I (NEB) site of the HITI backbone vector (Addgene, #87116) using the In-Fusion HD cloning kit

Key Difference: Tirzepatide (Mounjaro/Zepbound): Dual GIP/GLP-1 agonist Semaglutide (Wegovy/Ozempic): GLP-1 agonist only Effectiveness Difference: Tirzepatide: 15-22% average body weight loss Semaglutide: 10-15% average body weight loss Semaglutide is less potent but still highly effective and significantly more affordable than brand-name tirzepatide

Detka, J., & Gombik, K

For tirzepatide, 2.5 mg weekly
