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The most serious side effects of GLP-1 receptor agonists include gallbladder problems, pancreatitis, acute kidney damage, gastroparesis, bowel obstruction, and intestinal paralysis

Lack of correlation between gastroesophageal reflux disease symptoms and esophageal lesions after sleeve gastrectomy

Aldhaleei et al., for instance, found increased gastrointestinal (GI) adverse events in GLP-1RA users, which could contribute to nocturnal reflux and sleep disruption [17]

Some individuals may respond better to one form of TRT over the other in terms of symptom relief and overall well-being
