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In the authors anecdotal experience, when further uptitration is not tolerated, but treatment effects are noted, maintaining the patient at the lower tolerated dose may be preferable to discontinuation

Fourth, due to the absence of imaging, histological, or laboratory-based indices, such as the Fatty Liver Index on the TriNetX platform, this study relied on an ICD-10-CM-based definition to identify MASLD, which has been validated 34 and used in previous studies 35,36

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[DOI] [PMC free article] [PubMed] [Google Scholar] 90.Theilig F., Wu Q
