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One study published in the New England Journal of Medicine found that patients using semaglutide for weight loss lost an average of 14.9% of their body weight over 68 weeks

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The LEADER trial with liraglutide and the REWIND trial with dulaglutide did not show significant increases in retinopathy complications, though differences in trial design, patient populations, baseline retinopathy prevalence, and rates of glycemic improvement may explain these discrepant findings

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