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While the endocannabinoid system has its own cannabinoids, collectively referred to as endogenous cannabinoids , other exogenous (externally sourced) cannabinoids can interact with receptors: Phytocannabinoids (from plants) include tetrahydrocannabinol (THC), cannabidiol (CBD), and cannabinol (CBN)

A recent narrative review of observational studies [21] also suggested that combination therapy was associated with a lower risk of MACE, all-cause mortality, hospitalisation for heart failure, and kidney failure

The benefit of this method is that the patient does not experience an extended period of hypothyroidism as with hormone withdrawal

However, it is fundamental for patients to openly discuss their condition with a healthcare provider to determine the appropriate treatment based on their specific condition and needs