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Addressing sleep apnea (which weight loss often resolves) creates a positive feedback loop Exercise: Resistance training during GLP-1 therapy preserves muscle mass and improves body composition outcomes even when total weight loss is similar Hormonal factors (women): Perimenopausal hormonal changes affect how women respond to GLP-1 therapy

Choosing Healthy Fats: Sources like avocados, nuts, and olive oil are important for health

However, clinical data on both peptides reveal their efficacy

Semaglutide, by contrast, activates GLP-1 receptors in the brain and pancreas to reduce appetite, slow stomach emptying, and improve blood sugar control