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Clinical pharmacology of incretin therapies for type 2 diabetes mellitus: implications for treatment

When you're on GLP-1 medications, your appetite is naturally reduced, and foods high in fat and refined carbs can feel especially heavy

2 Establishes GLP-1RAs are engineered to overcome the rapid degradation of native GLP-1 through DPP-4resistant modifications and exposure-extending strategies such as fatty-acid acylation, enabling sustained receptor occupancy

2018;8(7):e019562
