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Discussion This review covers the importance of maintaining NAD + levels for cellular homeostasis and mitochondrial maintenance, as well as evaluating established and novel NAD + boosting strategies from simple supplementation of precursors to modulation of enzymes by drugs

Diarrhoea is an uncommon side effect of vitamin B12 supplementation, listed as a rare adverse reaction in UK product information for both oral and injectable preparations

[DOI] [PMC free article] [PubMed] [Google Scholar] 62.Ratner R.E., Want L.L., Fineman M.S., Velte M.J., Ruggles J.A., Gottlieb A., Weyer C., Kolterman O.G

Third-party testing provides some assurance of purity and identity