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Notably, three classes of bactericidal antibiotics-lactams, quinolones, and aminoglycosideshave been reported to induce the production of harmful hydroxyl radicals in gram-positive and gram-negative bacteria, a process that activates the Fenton reaction (Kohanski et al., 2007

Non-Age-Related Hearing Loss (Non-ARHL): included studies on hearing loss with identifiable etiologies (e.g., noise-induced, ototoxic, infectious, or congenital)

37 A systematic review that included three clinical trials with a total of 279 participants found incorporating antioxidant therapy with vitamins A, C, and E into treatment of sudden sensorineural hearing loss led to enhanced hearing gains

Rats fed with B12 deficient diet triggered NASH through activation of pro-inflammatory pathways with an imbalanced release of IL- 1, IL- 10, and MCP1 [19]