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Another group reported that disulfiram, but not its primary metabolite DDC, attenuated synaptic glutamate uptake in rat brain and in cultured neurons, resulting in higher extracellular levels of glutamate (81)

Neurology, 86(5), 491492

: Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat: A pooled analysis of two multicenter, double-blind placebo-controlled phase 3 trials with safety extension data

This decreases the calciumcalmodulin activation of myosin light-chain kinase, thereby decreasing smooth muscle contraction and favoring relaxation