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Varney, who has worked in obesity medicine for 16 years, explained that FDA-approved weight loss medications such as Ozempic and Wegovy are synthetic drugs designed to mimic naturally occurring peptides in the body, including insulin and glucagon-like peptide-1, or GLP-1

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doi: 10.3390/biomedicines10102476

The mucosal layer can also be attenuated as a result of reduced dietary fibre intake which encourages the growth of mucus-degrading species such as Bacteroides caccae and Akkermansia muciniphila (Desai et al