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This method is often used in hospitals to help people with serious health problems
Taking quercetin as an example, its copper-complexed form (CuQ) not only exhibits superior antioxidant activity compared to free quercetin but can also switch to a pro-oxidant state in the tumor microenvironment [256], inducing mitochondrial oxidative damage and DNA strand breaks
doi: 10.1002/1873-3468.14184 31
In vitro , Sirt1 protein expression was significantly increased in primary hepatocytes by NNMT overexpression and was significantly decreased in primary hepatocytes by NNMT knockdown [14]
