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We found that when IRE1 was depleted in MDA-MB-231 triple-negative breast cancer cells, these cells became significantly more resistant to ferroptotic cell death induced by either erastin, an inhibitor of the cystine-glutamate antiporter SLC7A11, or cystine depletion (Fig

Oxid Med Cell Longev 2021(1):8868941 Saba J et al (2022) Neuroinflammation in Huntingtons disease: a starring role for astrocyte and microglia

This is a severe, potentially life-threatening rash, most commonly resulting from a hypersensitivity reaction to a medication, which occurs in about 0.1% of bipolar patients treated with lamotrigine (Goldsmith 2004)

In another study, Hayashi and colleagues developed a D-monobody targeting the inflammation-related cytokine, monocyte chemoattractant protein-1 (MCP-1) 81
