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Its best to avoid combining it with strong actives like Vitamin C or retinol in the same routine to prevent reduced effectiveness

Misso, N

4 One thing to note, although there are pharmacologic differences among the different PPIs, resulting in differences in acid suppression 19 , for day-to-day practice PPIs, when given in standard doses, are generally considered equal when treating common conditions such as Gastro Esophageal Reflux Disease (GERD) or peptic ulcer disease (PUD)