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Description
Increased mitochondrial (mt)DNA copy number has been detected in the blood of patients with COPD along with a positive correlation to the number of pack-years smoking (73)

Furthermore, CISD2 was found to be effective in conditions such as IS-I/R and ICH (Yeh et al., 2022)

Changes in DNA damage repair genes may lead to chromosomal breakage, cytopathic effects, and the development of cancer, which increases the risk of POI

Front Cardiovasc Med 2019
