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Furthermore, the findings suggested that DAPA may attenuate HG-induced ferroptosis and mitigate histological damage and functional abnormalities in the kidneys of diabetic nephropathic mice, both in vivo and in vitro
In addition, copper increased glutathione oxidation through oxidative stress and reduced the degree of glutathione conjugation [40], resulting in the oxidation of catecholamines in vivo and subsequent cardiotoxicity
E., McLane L
