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Energy management and activity pacing for ME/CFS Energy management and activity pacing are widely recognized as first-line approaches for managing ME/CFS, particularly following the 2021 update of NICE guidelines, which recommended activity pacing as the only management strategy for ME/CFS [172]

The activity of sulfiredoxin in RBCs is sufficient to counteract the Prx II hyperoxidation that occurs during elimination of H 2 O 2 molecules resulting from hemoglobin (Hb) autoxidation

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