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The second occurs primarily in the kidney and forms the physiologically active 1,25-dihydroxyvitamin D [1,25(OH) 2 D], also known as calcitriol [1]
Additional recent technical advances that provide insights into the impact of brain-derived alcohol metabolism are the generation of pre-clinical models that allow the investigation of cell-type-specific ALDH2 distributions in a brain-region-specific manner (139)
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