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doi: 10.1007/s002040050367
Postsurgical protocols may be designed to cover the first 36 months of healing
S.KiskerO.DildaP.DonoghueN.ZhaoX.DecollogneS.et al (2003)
This therapy has shown limited efficacy, with survival benefits ranging from weeks to several months (165), which may be related to the fact that tumors can activate alternative pathways of angiogenesis, increase invasiveness and metastasis, or develop resistance to anti-angiogenic therapy by immune system inhibition (166)
