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doi: 10.1186/s41935-018-0038-x

Kawai et al., 2006)
In the case of I/R injury, systemic inflammation and the release of cytokines and LPS can enhance BBB permeability by breaking tight junctions between endothelial cells and by activating matrix metalloproteinases that breakdown the extracellular matrix (S-Pereira et al., 2012)

Most of the data on BPC-157 comes from controlled injury models across musculoskeletal, vascular, and soft tissue systems
