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A double-blind study by Michaelsson et al 44 of 40 patients with moderate to severe acne demonstrated no significant difference between papule, pustule, and comedone count in subjects treated with oral zinc sulfate versus oxytetracycline for 12 weeks

Improved outcomes were seen in patients with greater ultrafiltration flow rates

Cisneros-Tamayo M, Kempf I, Coton J, Michel V, Bougeard S, De Boissson C, Lucas P, Byon-Auboyer MH, Chiron G, Mindus C, Gautier-Bouchardon AV (2020) Investigation on eggshell apex abnormality (EAA) syndrome in France: isolation of Mycoplasma synoviae is frequently associated with Mycoplasma pullorum