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Primary Series The safety of the primary series Pfizer-BioNTech COVID-19 Vaccine was evaluated in participants 12 years of age and older in two clinical studies conducted in the United States, Europe, Turkey, South Africa, and South America

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Lifestyle Strategies Stress reduction: Yoga, meditation, and grounding can calm mast cells Dietary support: Focus on a low-histamine diet if symptoms flare often (avoiding alcohol, aged cheeses, fermented foods, and cured meats) Skin care: Use gentle, fragrance-free products and avoid hot showers that worsen histamine release When to Seek Immediate Care Most hives are harmless, but if you experience swelling of the lips, tongue, or throator difficulty breathingthis may indicate anaphylaxis , a medical emergency requiring immediate attention

Br J Nutr 83: 5936 pmid:10911766 8