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single nucleotide polymorphisms) and environmental factors ( Several studies have reported adverse effects of GBH and glyphosate exposure on female and male murine reproductive systems, at both low and environmentally relevant doses, including disruption of the hypothalamicpituitary-axis ( in vitro studies found alterations in sperm motility and mitochondrial functions in human sperm cells ( the European Food Safety Authority (EFSA) decided that glyphosate is unlikely to pose a carcinogenic risk to humans (EFSA 2015) ( The mechanisms of action of GBH and their metabolites are still under investigation