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Hit validation by transverse relaxation rate (R2) analysis To further characterise the two site-specific hits from the NMR fragment screen, we measured the transverse relaxation rate of the fragments with and without TRF1 TRFH

A potential wound-healing-promoting peptide from salamander skin

White lagoon The white lagoon is a High-Andean lagoon located within the Eduardo Abaroa Andean Fauna National Reserve, in southwestern Bolivia, in the department of Potos

We exploited the secured C-terminal modification site of each peptide, as discussed above, and prepared fluorescently labelled macrocycles aML5-Fluo, aMD4-Fluo and aMD5-Fluo via the -amino group of a lysine residue in a tag peptide at the C-terminus (Supplementary Table 2 and Supplementary Fig