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145 When a mother begins breastfeeding, the child receives the first direct dose of sulfur-containing antioxidants in breast milk assuming, of course, that the mother does not have errant genes that would lower her antioxidant levels

Use of Cu chelators and Cu ionophores have yielded encouraging anticancer activities in many preclinical models

Sildenafil has also shown a dose-dependent increase in H 2 S production in the human bladder dome that is reversed by CSE and CBS inhibitors [387]

The liver, which maintains the highest concentrations of glutathione in the body (5 to 10 mM), is the primary site of this detoxification activity