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Unlike growth hormone peptides (which work through the pituitary) or GLP-1 peptides (which work through gut and brain receptors), BPC-157 works primarily through a different mechanism: it upregulates growth hormone receptors in tendon cells, stimulates angiogenesis (the formation of new blood vessels), and modulates nitric oxide signaling all of which contribute to accelerated tissue repair and reduced inflammation

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[110] Additionally, the delivery of a calcium/calmodulin-dependent protein kinase-IV (CAMK4) inhibitor via nanoparticles ameliorated murine SLE

Some users run both: injectable for their primary healing goal, oral for GI protection during periods of anticipated drinking