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These alterations may be further exacerbated by oxidative stress and activation of profibrotic cytokines, such as transforming growth factor , ultimately contributing to the development of chronic kidney disease (82)

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Supplement Facts: Serving Size: 2 capsules Servings Per Container: 30 Amount Per Serving: Calcium (as Calcium D-Glucarate): 50 mg 3,3'-Diindolylmethane (DIM): 325 mg Calcium D-Glucarate: 250 mg Organic Broccoli (Brassica oleracea L.): 50 mg Black Pepper (Piper nigrum) Extract (fruit) (BioPerine): 5 mg *RI - Reference Intake Ingredients: Gelatin (Capsule), Microcrystalline Cellulose, Rice Powder, Magnesium Stearate, Silicon Dioxide