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All 5 selected trials applied B12 in at least one study arm (2, 10-13)

Compared to db/m mice, potential interactions between PT AQP4+ and the other PT subtypes (PTS1/2 and PTS3) including C3-CD81, FGG-ITGAV, and GC-LRP2 axis were only found in db/db mice (Fig

Importantly for MCS, the two receptors modulate and sensitize each other
