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this compound is autocyclized to form 5-OP when there is an insufficient amount of Cys as a substrate, as discussed above in the development of 5-oxoprolinuria

These local mediators cause intense myometrial contractions, uterine ischemia, and sensitization of nerve endings, culminating in severe pelvic pain
Mammalian glutathione peroxidases control acquisition and maintenance of spermatozoa integrity

To the best of our knowledge, it is not yet clear whether TVX induces direct cytotoxicity or whether metabolization and emerging toxic intermediates could primarily result in hepatocellular injury
