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Description
Analgesic effects may also be due to interference with descending serotonergic pain pathways through their activation

2,6 Epidemiology of hepatic sarcoidosis In biopsy and autopsy studies of patients with systemic sarcoidosis, liver involvement was found in about 5080%, 17 whereas only 1030% of patients presented with abnormal liver enzymes during laboratory testing

Metabolism 152 , 155768 (2024)
Monotherapies targeting lactate metabolism or the NAD + salvage pathway have demonstrated limited efficacy in clinical trials due to toxicity and redundant pathways that limit the therapeutic efficacy
