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Autism Spectrum Disorder ASD is a complex neurological and developmental condition that is defined by core symptoms of social communication difficulties, restricted interests, and repetitive behaviors [1]

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This finding was further corroborated by liver-specific IRE1 knockout, which exacerbates liver fibrosis and inflammation in high-fat diet-induced mice [43]

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SCFAs, including butyrate, play a crucial role in regulating the balance between Th 17 and regulatory T cells (Yoo et al., 2020)

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