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However, IR3 can sometimes act as an IGF1 mimetic and especially in cells overexpressing the IGF-1R (Kato et al, 1993)
It advanced to human clinical trials where it demonstrated effectiveness in the treatment of related ischemic injuries (Maples et al., 2004)
NOX5 (Figure 4) is a monomeric protein expressed in several tissues, mainly in the spleen and testis but also in vascular tissue, cells of the gastrointestinal tract, reproductive systems, and fetal organs
