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An advantage of on-column cleavage is the high level of purity obtained, but this comes at the expense of generally low yield due to less efficient protease cleavage and decreased control of the digestion conditions
They are slightly more expensive than "budget" vendors who don't provide COAs, but they are significantly more affordable than the legacy "medical-grade" research boutiques that charge a massive premium for their brand name
PloS One (2018) 13(10):e0206189
Package Deals : Some clinics offer discounted rates for package deals, which can help lower the cost of vitamin B12 injections
