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In a physical dependence assay (assessed at 6, 14, 42, and 72 hours after the conditioning treatment) shorter pre-convulsive latencies were noted in diazepam conditioned mice than in non-conditioned healthy mice following an isoniazid treatment forty-two and seventy-two hours after the conditioning treatment

Because less of the peptide is likely to be degraded in the stomach during oral studies, researchers may find that different dosing models are required to achieve the same systemic exposure compared to the acetate form

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