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Overall, for the vast majority of patients, biotin supplementation (whether oral or via injection) is free of significant side effects

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But as with any injection, a few mild effects are possible: Temporary redness or swelling at the injection site Mild nausea or digestive shifts Headache or light dizziness A brief boost in energy or restlessness (common if you're sensitive to B12) Bright yellow or orange urinetotally normal, just your body clearing excess B12 If anything feels off or persists, check in with your provider

Because B12 is primarily found in animal products (meat, fish, dairy, eggs), people following vegetarian or vegan diets may be at higher risk of deficiency