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Moreover, G289A and T337I mutations are located proximal to the ATP-binding pocket of the C-terminal domain, G289A would cause steric conflict with Ser293, and T337I would cause a hydrophobic patch on the protein surface and reduce protein solubility

The field of cancer metabolism subsequently revealed additional metabolic alterations in cancer by focusing on central carbon metabolism, including the citric acid cycle and pentose phosphate pathway

10.1016/j.febslet.2011.07.017 72 TakiguchiS.InoueK.MatsusueK.FurukawaM.TeramotoN.IguchiH

Bregman to discuss your condition, goals, and whether a peptide protocol alone or in combination with other regenerative or surgical treatments is appropriate for you