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Ginsenosides Rg3 and Rh2 from ginseng suppress breast and lung cancer growth, inhibit angiogenesis, and enhance chemotherapeutic drug sensitivity (e.g., cisplatin) by modulating Bcl-2 family proteins 185,186,187

Meanwhile, researchers discovered Mitochondria-targeted antioxidants (MTAXs) that can improve mitochondrial functions and antioxidant activity through the modulation of mitochondrial signaling pathways, including peroxisome proliferator-activated receptor (PPAR)-coactivator 1 (PGC-1), dynamin-related protein 1 (Drp1), mitochondrial fission protein 1 (Fis1), and Silent mating type information regulation 2 homolog 1 (SIRT-1), showing neuroprotective effects in HD

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