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Dopamine is a neurotransmitter heavily involved in motivation, reward, and focus
Studies show that weight loss of even 5-10% of total body weight will result in clinically significant benefits and will reduce the risk factors for many diseases

[DOI] [PubMed] [Google Scholar] 36.Chang C.H., Tsai W.C., Lin M.S., Hsu Y.H., Pang J.H.S

GLP-1 medications work largely by reducing appetite
