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(2021) identified a significant accumulation of cholesterol, specific phospholipids, and sphingolipids in the kidneys

Mayo Clinic proceedings, 88(6), 544551

Reference #18.47a71002.1784361891.8b4f8e1f

Unlike monoclonal antibodies that physically block PD-1/PD-L1 interactions, these agents reprogram the immunosuppressive milieu by simultaneously affecting tumor cells, tumor-associated macrophages, regulatory T cells, and inflammatory cytokine networks
