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Objective measures of strength are clear target outcomes in a disease of progressive weakness

L-Carnitina uma amina quaternria produzida de maneira natural pelo organismo, pelo fgado, rins e crebro, atravs dos aminocidos essenciais, como a lisina e metionina, por exemplo

Nezu J, Tamai I, Oku A, Ohashi R, Yabuuchi H, Hashimoto N, Nikaido H, Sai Y, Koizumi A, Shoji Y, Takada G, Matsuishi T, Yoshino M, Kato H, Ohura T, Tsujimoto G, Hayakawa J, Shimane M, Tsuji A: Primary systemic carnitine deficiency is caused by mutations in a gene encoding sodium ion-dependent carnitine transporter

Therefore, carnitine/acylcarnitine not only play roles in muscle energy metabolism but also participate in the whole-body energy balance and fatigue perception by affecting neuromuscular signaling, underscoring the potential importance of carnitine in exercise physiology, exercise recovery and performance improvement