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Description
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To develop cardiac insulin resistance, major factors such as hyperglycemia, hyperlipidemia, oxidative stress, inappropriate activation of sympathetic nervous system and the renin-angiotensin II-aldosterone system (RAAS), and dysregulated secretion of adipokines/cytokines are all significant contributors [139]
For immunohistochemistry (IHC) staining, after deparaffinization and rehydration, tissue sections were subjected to endogenous peroxidase blocking with 3% H 2 O 2 in PBS for 12 min at room temperature (RT) and permeabilization with 0.4% Triton X-100 for 5 min at RT
IL-5 receptor-mediated tyrosine phosphorylation of SH2/SHS-containing proteins and activation of bruton tyrosine and janus-2 kinases
