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In cellular models, BPC-157 was associated with activation of the FAK-paxillin pathway (focal adhesion kinase and an adhesion protein mediating cell attachment and movement)

[12] It is used in pediatric patients with intrinsic cobalamin metabolic diseases, vitamin B 12 -deficient patients with tobacco amblyopia due to cyanide poisoning, and patients with pernicious anemia who have optic neuropathy

The crypts contain the pluripotent stem cells that continually divide and differentiate themselves as they emigrate towards the tip of the villus, generating the different cell types of the epithelium (Figure 3)enterocytes, Goblet cells, enteroendocrine cells, and M cellsor remain in the crypts: Paneth cells [16]