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This leads to dilation of blood vessels and leakage of fluid, creating the characteristic swelling and redness
Curcumin and caffeic acid phenethyl ester stimulated the induction of heme oxygenase-1 in renal epithelial cells by inactivating the Nrf2-Keap1 complex, leading to enhanced binding of Nrf2 to resident ho-1 AREs [20]
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