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Hair loss also occurs at the crown, which can eventually lead to partial or complete baldness

For instance, in salicylate-induced tinnitus rats, significant upregulation of the microglial marker Iba1 occurs in the primary AC and medial geniculate body, and significant upregulation of the astrocytic marker GFAP occurs in the primary AC, alongside increased morphological complexity indicative of an activated state (Xia et al., 2020)

These limitations highlight the need for adequately powered, long-term randomized trials specifically designed to evaluate thyroid outcomes in different KD variants

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