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In a model with isolated hearts perfused using the Langendorff technique and with 30 min of global ischaemia and 120 min of reperfusion, the RSV also showed a beneficial effect [64]

On the other hand, a considerable although short-lasting increase in intraocular pressure may trigger or contribute to the major noxious process seen to progress with the L-NAME retrobulbar application and the supposed failure of NO-system adaptive capabilities [13]