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In the aging process, differently than in the younger population, accumulation of mitochondria DNA mutations, impairment of oxidative phosphorylation and an imbalance in the expression of antioxidant enzymes result in further overproduction of ROS

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Medicine (Baltimore) 12:40174024 Ethics declarations Conflict of interest On behalf of all authors, the corresponding author states that there is no conflict of interest

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References 160162 highlight the effect of the tumour microenvironment on effector T cell function

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